Ayurveda concept of pharmacokinetics and pharmacodynamics towards drug action: A review
Keywords:
Ayurveda, Pharmacokinetic, Pharmacodynamic, VipakaAbstract
The pharmaceutical terms pharmacokinetic define as process “what body does to the drug” means biological transformation of drug molecule inside the body. Similarly another term pharmacodynamic defines as process “what drug does to the body” means pharmacological action of drug. The classic Indian system of health management Ayurveda suggested different approaches for the restoration of normal health and treating diseases. As per ayurveda the natural drugs exerts their action by virtue of their Guna, Rasa, Vipaka, Prabhava and Virya. These properties of drugs contribute towards the pharmacodynamic profile of ayurveda drugs. The process of biotransformation of drug in ayurveda can be described as Vipaka which relates pharmacokinetic transformation of natural drugs. The ayurveda perspectives on drug’s action need to be explored with modern concepts therefore present article summarizes pharmacokinetic & pharmacodynamic aspects of drugs with reference to Ayurveda principles and theories
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